Product Development Scientist.

Company Description

Ori Biotech is on a mission to enable widespread patient access to life-saving cell and gene therapies.

Ori launched IRO®, a next-generation CGT manufacturing platform, as a first step towards achieving this mission. The IRO platform is designed to automate better biology and accelerate therapy development to help make these treatments more affordable and widely available to patients.

Scientific breakthroughs continue to be made in cell and gene therapy across a wide range of diseases, including cancer and rare genetic diseases. Despite these advancements, it is estimated that more than 95% of patients who could benefit from this new class of life-saving therapies are left without access.

The challenge is that these transformative treatments are difficult and expensive to manufacture due to the high cost of goods and low throughput limiting the ability to meet patient demand.

This is where Ori Biotech comes in. Our team of leading gene therapy and life sciences veterans are working in collaboration with industry partners to develop innovations that deliver exceptional biology while reducing the time and cost to develop and manufacture cell therapies, to help enable widespread patient access to life-saving cell and gene therapies.

With the commercial launch of IRO®, Ori is in a rapid growth phase backed by some of the top VCs in the US and UK. We are looking for trailblazers, visionaries and the naturally inquisitive; those who can challenge and those who can inspire at this very exciting time.

This is an excellent time to join our world-class team and to be an integral part of changing history by helping to ensure patient access to CGT treatments.

Job Description

We are seeking an experienced and motivated Scientist with a strong background in product development of cell and gene therapy (CGT) processing technologies to join our dynamic Scientific Team. The successful candidate will plan and execute product and process development experiments to develop, characterise, and optimise Ori’s CGT processing technologies. This role requires a hands-on approach to experimental work, data analysis, and close collaboration with technical, engineering, and cross-functional teams to develop robust and scalable cell processing technologies.

Key Responsibilities

• Responsible for designing and executing the biological testing strategy and providing end-user perspective to guide novel product development.
• Conduct comprehensive product characterisation to assess system performance, reproducibility, and scalability.
• Perform biological testing and data analysis to inform product development and optimisation strategies.
• Collaborate closely with technical and engineering teams to integrate experimental findings into product design and manufacturing processes.
• Optimise workflows to enhance efficiency and consistency.
• Utilise different root cause analysis methods for solving technical challenges.
• Document research activities clearly and thoroughly, analyse trends, and present findings to internal teams and stakeholders.
• Ensure all experimental work complies with Ori’s regulatory, quality, and health and safety standards.
• Author and adhere to Standard Operating Procedures (SOPs).
• Assist in maintaining laboratory equipment and the environment.
• Attend weekly R&D meetings and report results to the broader team as required.
• Stay informed about the latest advancements in the field.

Experience

• 3+ years’ experience in product development or R&D within cell and gene therapy manufacturing technology.
• Strong knowledge of bioprocessing principles, advanced manufacturing techniques, and/or automation.

Skills

• Creative and critical thinking skills to develop innovative solutions.
• Excellent oral and written communication skills for effective collaboration and reporting.
• Strong attention to detail with the ability to work quickly and accurately.
• Agile and proactive approach to working within a small team.
• Initiative-driven, with the ability to make informed decisions while keeping key stakeholders updated.
• Proficient in experimental design, ensuing appropriate controls and reproducibility.
• Excellent organisational and project management skills.
• Stays up to date with the latest advancements and best practices.
• Ability to engage constructively with colleagues across various departments to achieve shared objectives.
• Passionate about improving patient outcomes through scientific innovation.

Contract Type: Permanent