R&D Consumables Design Engineer.

Company Description

Ori Biotech is on a mission to enable widespread patient access to life-saving cell and gene therapies.

Ori launched IRO®, a next-generation CGT manufacturing platform, as a first step towards achieving this mission. The IRO platform is designed to automate better biology and accelerate therapy development to help make these treatments more affordable and widely available to patients.

Scientific breakthroughs continue to be made in cell and gene therapy across a wide range of diseases, including cancer and rare genetic diseases. Despite these advancements, it is estimated that more than 95% of patients who could benefit from this new class of life-saving therapies are left without access.

The challenge is that these transformative treatments are difficult and expensive to manufacture due to the high cost of goods and low throughput limiting the ability to meet patient demand.

This is where Ori Biotech comes in. Our team of leading gene therapy and life sciences veterans are working in collaboration with industry partners to develop innovations that deliver exceptional biology while reducing the time and cost to develop and manufacture cell therapies, to help enable widespread patient access to life-saving cell and gene therapies.

With the commercial launch of IRO®, Ori is in a rapid growth phase backed by some of the top VCs in the US and UK. We are looking for trailblazers, visionaries and the naturally inquisitive; those who can challenge and those who can inspire at this very exciting time.

This is an excellent time to join our world-class team and to be an integral part of changing history by helping to ensure patient access to CGT treatments.

Job Description

This is an exciting opportunity for an enthusiastic individual to join our high-performing R&D Engineering team, focusing on Consumables.

In this role, you will be responsible for understanding customer needs, capturing design requirements, and developing conceptual designs that both look and function as intended. You will also support the development of business cases and the transfer into manufacturing, including testing and validating plastic consumables for use in Ori’s Cell and Gene Therapy manufacturing platforms.

Your work will involve collaboration with stakeholders across the business.

Key Responsibilities

• Understanding and capturing customer and business needs and requirements in URS/FRS.
• Creating and evaluating novel solutions through, design (looks-like, works-like), prototyping and testing.
• Quantifying and understanding the business implications of new ideas and comparing Life Cycle Analysis for leading approaches against customer needs.
• Providing documentation that is compliant with Ori’s QMS ISO13485 complaint.
• Clear communication and document control with a willingness to work with other business
  functions.

Experience

• +5 years of proven design experience for plastic consumables (ideally as part of an electro-mechanical product)
• Strong knowledge of manufacturing techniques (e.g. injection moulding, heat sealing, sterilisation) of bioprocessing consumables. Experience in the CGT field is advantageous.
• Working knowledge of Engineering design packages e.g. SolidWorks 3D CAD, PDM, Rhino, Keyshot.
• Experience working cross-functionally to create meaningful business cases and project definitions/requirements.
• Demonstratable experience in early QMS phase development in a BioTech or MedTech company.
• Experience in the complete lifecycle of product development in a highly regulated industry.

Skills

• Enthusiastic and passionate with a love of technology and product design.
• Self-motivated, persistent, and collaborative, you have a “can-do” attitude and approach.
• A keen eye for detail.
• Tenacious and persistent with a determination to go the extra mile to see all projects through to completion.
• Equally capable of working independently or as part of a team.
• An excellent communicator, you are adept at information sharing and contributing towards an open, positive team atmosphere.
• Keeps up to date with professional knowledge, expertise, and best practice.
• You are excited about the prospect of making a real difference in patient outcomes.

Qualifications

• BSc/BEng, MSc/MEng, PhD within an Engineering or Life Science subject.

Contract Type: Permanent